Why Do ‘Black’ Pacific Populations of Melanesia Have Blond Hair?
Posted by addisethiopia / አዲስ ኢትዮጵያ on May 6, 2012
Blond hair is relatively common in the Solomon Islands, even though the skin pigmentation of Melanesian peoples is relatively dark.
Naturally blond hair is rare in humans and found almost exclusively in Europe and Oceania. Here, we identify an arginine-to-cysteine change at a highly conserved residue in tyrosinase-related protein 1 (TYRP1) as a major determinant of blond hair in Solomon Islanders. This missense mutation is predicted to affect catalytic activity of TYRP1 and causes blond hair through a recessive mode of inheritance. The mutation is at a frequency of 26% in the Solomon Islands, is absent outside of Oceania, represents a strong common genetic effect on a complex human phenotype, and highlights the importance of examining genetic associations worldwide.
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Cortisone injections directly in to the spinal column (called `epidural’, due to the fact they are injected beneath the dura, and that is the thin layer of membrane around the spinal cord) may well be applied to provide short-term discomfort relief, although long-term utilization of steroids will not be recommended.
Vijaya said
Actually this mutation is not absent outside of oceana. We have this mutation in both India and Sri Lanka.